E-Atx vs Mini-Itx PC Cases: Which Should You Buy?
As an Amazon Associate we earn from qualifying purchases. Links on this page are affiliate links.
Choosing the right E-ATX vs Mini-ITX PC case depends on your build goals. Both the ASUS TUF Gaming GT501 and the SilverStone SG13B are designed to house internal components securely. They differ significantly in scale and capacity. The ASUS model is a full-tower built for large motherboards and extensive cooling options. The SilverStone unit is a small form factor case optimized for compact Mini-ITX builds. Your choice hinges on whether you prioritize expansion space or a smaller footprint.
Key differences
| Aspect | ASUS TUF Gaming E-ATX Full-Tower Case | SilverStone Small Form Factor Mini-ITX Case |
|---|---|---|
| Motherboard Support | E-ATX | Mini-ITX, Mini-DTX |
| Tower Size | Full-Tower | Small Form Factor |
| Radiator Support | Up to 360mm | 120mm, 140mm |
| Side Panel | Tempered Glass | not listed |
| Weight | 26.2 pounds | 6 pounds |
Which one should you choose?
Choose ASUS TUF Gaming E-ATX Full-Tower Case if
- You need space for E-ATX motherboards and multiple expansion slots.
- You want to install large 360mm liquid cooling radiators.
- You prefer a case with a tempered glass side panel for visibility.
Choose SilverStone Small Form Factor Mini-ITX Case if
- You are building a compact system with Mini-ITX or Mini-DTX boards.
- You want a lightweight case that is easy to transport.
- You have limited desk or floor space for your computer.
Verdict: The ASUS TUF Gaming GT501 suits builders who need maximum expansion and cooling flexibility. The SilverStone SG13B is the better fit for those prioritizing a small footprint and portability. Select the case that matches your motherboard size and physical space constraints.
E-ATX Versus Mini-ITX Case Specs
Motherboard Support
The ASUS TUF Gaming GT501 supports E-ATX motherboards, allowing you to install larger boards with more expansion slots and features. This case is ideal for users who need extensive connectivity or plan to use high-end workstations. In contrast, the SilverStone SG13B is designed for Mini-ITX and Mini-DTX motherboards. These smaller boards limit the number of expansion slots but reduce the overall footprint. Your choice depends on whether you prioritize expandability or compactness. The ASUS offers more room for large boards, while the SilverStone enforces a smaller form factor.
Tower Size
Size is a major differentiator between these two cases. The ASUS TUF Gaming GT501 is a full-tower case, providing ample internal space for large components and extensive cabling. This extra volume helps with airflow and makes installing multiple drives easier. The SilverStone SG13B is a small form factor case, measuring significantly smaller in every dimension. It is designed to fit on a desk or in tight spaces. If you have limited desk space, the SilverStone is the practical choice. If you have a dedicated area for a large build, the ASUS full-tower offers more flexibility.
Radiator Support
Cooling options vary greatly between these models. The ASUS TUF Gaming GT501 supports up to a 360mm radiator, which can be mounted at the top or front. This allows for robust liquid cooling solutions to handle high heat output from powerful components. The SilverStone SG13B supports smaller 120mm or 140mm single-fan all-in-one liquid coolers. This limits your cooling performance options but keeps the build compact. If you plan to use high-performance CPUs that generate significant heat, the ASUS provides better cooling headroom. For moderate builds, the SilverStone is sufficient.
Side Panel
The ASUS TUF Gaming GT501 features a 4mm-thick smoked, tempered-glass full-view side panel. This allows you to showcase your internal components and RGB lighting clearly. The SilverStone SG13B does not have a tempered glass side panel listed in its specifications. Instead, it uses a faux aluminum front panel, which gives it a different aesthetic. If you want to display your hardware, the ASUS is the clear choice. If you prefer a more enclosed look or do not care about visibility, the SilverStone works well.
Weight and Portability
Weight impacts how you move and set up your case. The ASUS TUF Gaming GT501 weighs 26.2 pounds, making it quite heavy. However, it includes ergonomic woven-cotton carry handles to help you transport it safely. The SilverStone SG13B weighs only 6 pounds, making it much lighter and easier to move around. This lightness is beneficial if you plan to move your PC frequently or have limited strength. The ASUS is built for stability in a fixed location, while the SilverStone offers greater mobility due to its low weight.
Which PC Case Suits Your Build
Users needing maximum expansion and cooling
The ASUS TUF Gaming GT501 supports E-ATX motherboards and offers seven traditional expansion slots. It accommodates large 360mm radiators and includes pre-drilled holes for water pump reservoirs. You get ample space for high-end components and extensive airflow options, making it ideal for complex, high-performance workstations.
Builders prioritizing compact form factors
The SilverStone SG13B is a small form factor case designed for Mini-ITX and Mini-DTX motherboards. It measures just 12 by 10 by 14 inches, fitting easily into tight spaces. Despite its size, it supports standard-length expansion cards up to 10.5 inches and includes storage for both 2.5 and 3.5-inch drives.
Those valuing portability and weight
If you move your rig often, the SilverStone SG13B weighs only six pounds. It is significantly lighter than the ASUS GT501, which weighs 26.2 pounds. The compact dimensions and low weight make the SilverStone unit much easier to transport or store when you are not using your PC.
Quick picks
| # | Product | Best for | Price |
|---|---|---|---|
| 1 | ASUS TUF Gaming E-ATX Full-Tower Case | E-ATX builds requiring extensive cooling support | Check price of ASUS TUF Gaming E-ATX Full-Tower Case on Amazon |
| 2 | SilverStone Small Form Factor Mini-ITX Case | Mini-ITX builds with short GPUs | Check price of SilverStone Small Form Factor Mini-ITX Case on Amazon |
The products compared
ASUS TUF Gaming E-ATX Full-Tower Case
Best for: E-ATX builds requiring extensive cooling support
- Motherboard Support
- E-ATX (what this guide is about)
- Case Type
- Full-Tower
- Side Panel
- Tempered Glass
- Radiator Support
- 360mm
- Max GPU Length
- 420mm
- Fan Size
- 120mm, 140mm
View on Amazon: ASUS TUF Gaming E-ATX Full-Tower Case Affiliate link
The ASUS TUF Gaming GT501 is a full-tower case designed for E-ATX motherboards. It features a metal chassis and a 4mm tempered glass side panel. The case includes three 120mm RGB fans and one 140mm rear fan. It supports up to 360mm radiators for liquid cooling. Ergonomic handles allow you to move the heavy unit easily. This case suits builders needing maximum expansion space.
Pros
- Supports E-ATX motherboards for maximum motherboard compatibility
- Includes four pre-installed fans (three 120mm, one 140mm)
- Supports up to 360mm radiators for liquid cooling
- Features a 4mm tempered glass side panel
- Has ergonomic woven-cotton carry handles
Cons
- Full-tower design requires significant desk or floor space
- Weighs 26.2 pounds, making it heavy to move
- Dimensions are listed in inches, which is unusual for case size
Good fit if
- You need a case that supports E-ATX motherboards
- You want pre-installed fans for immediate airflow
- You plan to use large liquid cooling radiators
Skip if
- You are building a Mini-ITX system
- You need a compact case for small desks
- You prefer a lightweight case for frequent transport
Verdict: The ASUS TUF GT501 E-ATX Full-Tower is a spacious option for builders who need E-ATX support and robust cooling potential. It fits users who prioritize expansion slots and liquid cooling capacity over compact form factors.
SilverStone Small Form Factor Mini-ITX Case
Best for: Mini-ITX builds with short GPUs
- Motherboard Support
- Mini-ITX (what this guide is about)
- Case Type
- Small Form Factor
- Radiator Support
- 120mm, 140mm
- Max GPU Length
- 10.5 inches
- Dimensions
- 14 × 12 × 10 inches
- Weight
- 6 pounds
View on Amazon: SilverStone Small Form Factor Mini-ITX Case Affiliate link
The SilverStone SG13B is a small form factor case designed for Mini-DTX and Mini-ITX motherboards. It supports ATX power supplies and expansion cards up to 10.5 inches long. You can install 120mm or 140mm AIO liquid coolers. It also holds 2.5-inch and 3.5-inch drives. This compact build suits users who need a tiny footprint for standard components.
Pros
- Supports Mini-DTX and Mini-ITX motherboards
- Accepts expansion cards up to 10.5 inches
- Compatible with ATX power supplies
- Fits 120mm or 140mm AIO coolers
Cons
- Max GPU length is limited to 10.5 inches
- No support for standard ATX motherboards
- Only holds single fan radiators
Good fit if
- You use a Mini-ITX or Mini-DTX motherboard
- You need a case under 12 inches wide
- You plan to use an ATX power supply
Skip if
- You require an E-ATX motherboard slot
- Your graphics card exceeds 10.5 inches
- You need multiple drive bays
Verdict: SilverStone SG13B Mini-ITX Case is a compact solution for Mini-ITX builds. It fits users who prioritize a small footprint and ATX PSU compatibility over large GPU clearance.
Specifications side by side
| Spec | ASUS TUF Gaming E-ATX Full-Tower Case | SilverStone Small Form Factor Mini-ITX Case |
|---|---|---|
| Motherboard Support | E-ATX | Mini-DTX, Mini-ITX |
| Case Type | Full-Tower | Small Form Factor |
| Side Panel | Tempered Glass | not stated |
| Radiator Support | 360mm | 120mm, 140mm |
| Max GPU Length | 420mm | 10.5 inches |
| Tower Size | Full-Tower | Small Form Factor |
| Fan Size | 120mm, 140mm | not stated |
| Use | Gaming | not stated |
| Lighting | RGB | not stated |
| Compatible Device | Radiator | not stated |
| Dimensions | 215 × 98.8 × 217 inches | 14 × 12 × 10 inches |
| Weight | 26.2 pounds | 6 pounds |
| Size | EATX | not stated |
| Color | GT501|Grey | SG13B-Q-V1 |
| Model | GT501/GRY/WITH HANDLE | SG13B-Q |
Frequently asked questions
Can I fit a full-size ATX motherboard in an E-ATX case?
Yes, you can. E-ATX cases are designed with larger mounting holes to accommodate the biggest motherboards. This design also allows you to install smaller ATX or Micro-ATX boards without issue. You gain flexibility in your component choices while maintaining a spacious interior for other hardware.
How much bigger is an E-ATX case than a Mini-ITX case?
E-ATX cases are significantly larger. The ASUS TUF Gaming GT501 measures 98.8 inches wide, 217 inches high, and 215 inches long. It weighs 26.2 pounds. In contrast, the SilverStone SG13B Mini-ITX case is much smaller, measuring 12 inches wide, 10 inches high, and 14 inches long. It weighs only 6 pounds.
Which case is better for a small desk setup?
The SilverStone SG13B is the better choice for compact spaces. As a Small Form Factor case, it has a tiny footprint. Its dimensions are 12 by 10 by 14 inches. This allows it to fit easily on most desks. The E-ATX full-tower option is too large for tight spaces.
Does an E-ATX case support more expansion slots?
E-ATX cases generally support more expansion slots due to their size. The ASUS TUF Gaming GT501 supports E-ATX motherboards, which often include more slots. This provides greater connectivity for additional cards. Mini-ITX cases typically limit you to fewer slots due to their compact internal layout.
Can I use an ATX power supply in a Mini-ITX case?
Yes, you can. The SilverStone SG13B is designed to be compatible with standard ATX power supplies. This compatibility allows you to use widely available PSU models. It helps keep costs down while maintaining the small form factor benefits of the Mini-ITX design.
Is an E-ATX case good for water cooling?
E-ATX cases are excellent for water cooling. The ASUS TUF Gaming GT501 offers robust cooling potential. It can accommodate large radiators, such as 360mm units. The spacious interior also includes pre-drilled holes for water pump reservoirs. This makes it ideal for complex liquid cooling loops.

